Medical Microbiology in the Genomics Era
Section A Answer one question in this section
1. Assess the British HIV Association guidelines to treat HIV and evaluate the mechanism of action of the two classes or reverse transcriptase drug inhibitors to treat HIV infections and provide named examples of each drug class .
2. Compare and contrast the infections caused by influenza A and SARS-CoV-2 viruses. Include in your answer examples of how both viruses subvert and evade the immune response.
Section B Answer one question in this section
3. Mycobacterium tuberculosis, the causative agent of human tuberculosis is a non-motile, non-spore forming bacterium with some unusual features. Evaluate the contribution of each of the following features of mycobacteria to TB diagnostics, disease progression and treatment:
a) cell wall
b) bacterial life cycle
c) growth rate
(equal marks for each component).
4. Examine the concept of anti-malarial drug resistance and how does it develop (70%), and assess why is this of increasing importance in relation to public health .
Section C Answer one question in this section
5. Compare and contrast the laboratory diagnosis of two, named bacterial sexually transmitted infections.
6. Write short notes on mobile genetic elements in bacteria and examine the role of specific named examples of MGEs that contribute to resistance to betalactams in MRSA and resistance to polymyxins in E. coli .
END OF TIMED ASSESSMENT
