Tuskegee Study of Untreated Syphilis in the Negro Male
1. A) Identify the initial rationale that prompted the study and then the major change that occurred;
B) Describe the two profound ethical dilemmas within the study.
2. A) Define the significance of this study: Compare the perceived benefit at the time versus the risks;
B) Describe the key positive and the key negative legacies of Tuskegee.
3. A) Define each of the following ethical principles as it relates to research and medicine
B) Provide example(s) of the ethical breach(es) for each principle in the study
C) Compare/explain current advances in research; and where applicable, in patient care
• Informed consent
• Autonomy
• Beneficence / Nonmaleficence
• Veracity
• Confidentiality
• Justice
• Utility
• Paternalism
4. Define at least five protections instituted that would ensure this would not be repeated today?
