Discuss the influence of excipients upon drug release, comparing the modified-release formulation identified and immediate release formulations.
Background Pfi-Pharma, a major pharmaceutical company holds the recently expired patent for Brand X®, a cDMARD formulated as a modified-release preparation in the management of Rheumatoid Arthritis. Brand X® is delivered orally at a dose of 200mg once daily. Originally Brand X® was formulated as an immediate release formulation, this was quickly identified as being […]