How does this study exemplify the role of the micro-environment on cancer cells?Based on what was covered in the module, can you briefly describe another example?
To define the mechanisms regulating cell survival and growth of HNSCC, HSC–3 cells were subjected to cell culture in 3 dimensions (3D culture) as multicellular aggregates (MCA) also called spheroids. ErbB3 expression was significantly increased following MCA formation compared with monolayer (ML) culture at 24 h (not shown here).To determine the importance of elevated ErbB3 […]