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Describe the four processes in the pharmacokinetic phase. What factors influence each process? Include first-pass effect, protein binding, and free drug in your answer.

Describe the thermodynamics phase. Include onset, peak, duration, peak and trough levels.
What nursing interventions are necessary when a patient takes a medication that must be monitored by peak & trough levels? Why?
Explain how the nursing process is used to safely give medications to patients.
Include intent citations and references.

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