Set a list of concentrations for both acetylcholine and pilocarpine. With the help of dilution formula in the virtual organ bath software, work out the volumes required from the appropriate stock solutions.
1. Discuss
• What is Acetylcholine and how does it produce contraction of the smooth muscle?
• What is pilocarpine ? what is its mechanism of action? discuss briefly its therapeutic applications.
• Identify two drugs that can be used for their effect on smooth muscles within the body and briefly discuss the following:
– the mechanism of action
– drug-drug interaction
– therapeutic application
