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What is pilocarpine ? what is its mechanism of action? discuss briefly its therapeutic applications.What is Acetylcholine and how does it produce contraction of the smooth muscle?

Set a list of concentrations for both acetylcholine and pilocarpine. With the help of dilution formula in the virtual organ bath software, work out the volumes required from the appropriate stock solutions. 1. Discuss • What is Acetylcholine and how does it produce contraction of the smooth muscle? • What is pilocarpine ? what is […]

Briefly describe the mechanisms of Acetylcholine Synthesis, packaging and reuptake. Choose one of these processes and critically discuss the impact it has on behaviour.

Description choose one question from section A to answer Section A: 1. Briefly outline the mechanisms of GABA synthesis and critically discuss the role alteration in the function of the enzyme GAD may play in epilepsy/seizure susceptibility 2. Briefly describe the mechanisms of Acetylcholine Synthesis, packaging and reuptake. Choose one of these processes and critically […]

With reference to receptor signalling processes, discuss how acetylcholine can give rise to these opposing physiological effects in the heart and gastrointestinal tract.

Q1: Acetylcholine acting through muscarinic receptors reduces heart rate but increases gastrointestinal smooth muscle contraction. With reference to receptor signalling processes, discuss how acetylcholine can give rise to these opposing physiological effects in the heart and gastrointestinal tract. (100% marks) Q2: Carvedilol (Coreg) is a beta-blocker used for treating hypertension. Carvedilol is metabolised by CYP2D6. […]

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