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Distinguish between positive and negative feedback mechanisms such as the effect of oxytocin (in labour) and the control of Ca2+ (linked to osteoporosis) respectively.

1. Understand the concept of homeostasis in the human body 1.1 Define the term homeostasis and apply this to the nervous and endocrine systems. 1.2 Characterise the three classes of neurones and explain how they work in a simple reflex arc. 1.3 Explain the propagation of a nerve impulse and synaptic transmission. 2. Understand the […]

Discuss disorders of mineral ion metabolism due to alterations in CaSR expression and/or function.

Description Basically make an essay out of the attached powerpoint – Understand how extracellular free ionised Ca2+ concentration is monitored, and the relative contributions of the parathyroid and kidney calcium-sensing receptor, CaSR – Discuss disorders of mineral ion metabolism due to alterations in CaSR expression and/or function. – Discuss the discovery of positive allosteric modulators […]

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